The 2013 Grand Prix of the Americas was the second round of the 2013 MotoGP season. It was held at the Circuit of the Americas in Austin, Texas on April 21, 2013. This was the first GP race at the circuit.

Marc Marquez won his first MotoGP race, in which was only his second race in the top level, and became the youngest ever rider to win a MotoGP race.